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Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) alleviate excessive autophagy of ovarian granular cells through VEGFA/PI3K/AKT/mTOR pathway in premature ovarian failure rat model

BACKGROUND: Premature ovarian failure (POF) is one of the leading causes of female infertility and is accompanied by abnormal endocrine, seriously affecting female quality of life. Previous studies have demonstrated that mesenchymal stem cells (MSCs) transplantation is a promising therapeutic strate...

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Detalles Bibliográficos
Autores principales: Dai, Wenjie, Yang, Hong, Xu, Bo, He, Tiantian, Liu, Ling, Ma, Xiaoqian, Ma, Jiaxue, Yang, Guoqin, Si, Rui, Pei, Xiuying, Du, Xing, Fu, Xufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542694/
https://www.ncbi.nlm.nih.gov/pubmed/37777781
http://dx.doi.org/10.1186/s13048-023-01278-z