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Islet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell

Type 1 diabetes results from the poorly understood process of islet autoimmunity, which ultimately leads to the loss of functional pancreatic beta cells. Mounting evidence supports the notion that the activation and evolution of islet autoimmunity in genetically susceptible people is contingent upon...

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Detalles Bibliográficos
Autores principales: Thompson, Peter J., Pipella, Jasmine, Rutter, Guy A., Gaisano, Herbert Y., Santamaria, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542715/
https://www.ncbi.nlm.nih.gov/pubmed/37488322
http://dx.doi.org/10.1007/s00125-023-05970-z