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Aging impairs the ability of vascular endothelial stem cells to generate endothelial cells in mice

Tissue-resident vascular endothelial stem cells (VESCs), marked by expression of CD157, possess long-term repopulating potential and contribute to vascular regeneration and homeostasis in mice. Stem cell exhaustion is regarded as one of the hallmarks of aging and is being extensively studied in seve...

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Detalles Bibliográficos
Autores principales: Shimizu, Shota, Iba, Tomohiro, Naito, Hisamichi, Rahmawati, Fitriana Nur, Konishi, Hirotaka, Jia, Weizhen, Muramatsu, Fumitaka, Takakura, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542733/
https://www.ncbi.nlm.nih.gov/pubmed/37563497
http://dx.doi.org/10.1007/s10456-023-09891-8