Engineered small extracellular vesicles loaded with miR-654-5p promote ferroptosis by targeting HSPB1 to alleviate sorafenib resistance in hepatocellular carcinoma

Sorafenib (sora) is the initial therapy for patients with progressive hepatocellular carcinoma (HCC), but the emergence of drug resistance has seriously impacted its therapeutic efficacy. However, the mechanism of sora resistance remains unclear, and effective strategies to overcome drug resistance...

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Detalles Bibliográficos
Autores principales: Sun, Jiao, Liu, Qi, Jiang, Yanfang, Cai, Zhihui, Liu, Hui, Zuo, Huaiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542782/
https://www.ncbi.nlm.nih.gov/pubmed/37777559
http://dx.doi.org/10.1038/s41420-023-01660-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542782/
https://www.ncbi.nlm.nih.gov/pubmed/37777559
http://dx.doi.org/10.1038/s41420-023-01660-2

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