Platelet phosphatidylserine is the critical mediator of thrombosis in heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is a severe immune-mediated prothrombotic disorder caused by antibodies (Ab) reactive to complexes of platelet factor 4 and heparin. Platelets (PLT) and their interaction with different immune cells contribute to prothrombotic conditions in HIT. However, the ex...

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Detalles Bibliográficos
Autores principales: Zlamal, Jan, Singh, Anurag, Weich, Karoline, Jaffal, Hisham, Uzun, Günalp, Pelzl, Lisann, Althaus, Karina, Bakchoul, Tamam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542843/
https://www.ncbi.nlm.nih.gov/pubmed/37102605
http://dx.doi.org/10.3324/haematol.2022.282275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542843/
https://www.ncbi.nlm.nih.gov/pubmed/37102605
http://dx.doi.org/10.3324/haematol.2022.282275

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