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Platelet phosphatidylserine is the critical mediator of thrombosis in heparin-induced thrombocytopenia
Heparin-induced thrombocytopenia (HIT) is a severe immune-mediated prothrombotic disorder caused by antibodies (Ab) reactive to complexes of platelet factor 4 and heparin. Platelets (PLT) and their interaction with different immune cells contribute to prothrombotic conditions in HIT. However, the ex...
Autores principales: | Zlamal, Jan, Singh, Anurag, Weich, Karoline, Jaffal, Hisham, Uzun, Günalp, Pelzl, Lisann, Althaus, Karina, Bakchoul, Tamam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542843/ https://www.ncbi.nlm.nih.gov/pubmed/37102605 http://dx.doi.org/10.3324/haematol.2022.282275 |
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