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Acute and Sub-chronic Anticonvulsant Effects of Edaravone on Seizure Induced by Pentylenetetrazole or Electroshock in Mice, Nitric Oxide Involvement

BACKGROUND: Edaravone is an anti-stroke medication that may have nitric oxide (NO) modulating properties. This study evaluated the role of NO in the acute and sub-chronic anticonvulsant effects of edaravone in murine models of seizures induced by intraperitoneal (IP) or intravenous (IV) injections o...

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Detalles Bibliográficos
Autores principales: Moezi, Leila, Pirsalami, Fatema, Dastgheib, Mona, Oftadehgan, Somayeh, Purkhosrow, Azar, Sattarinezhad, Elahe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542921/
https://www.ncbi.nlm.nih.gov/pubmed/37791336
http://dx.doi.org/10.30476/ijms.2022.94177.2544