Structural basis of transcription: RNA Polymerase II substrate binding and metal coordination at 3.0 Å using a free-electron laser

Catalysis and translocation of multi-subunit DNA-directed RNA polymerases underlie all cellular mRNA synthesis. RNA polymerase II (Pol II) synthesizes eukaryotic pre-mRNAs from a DNA template strand buried in its active site. Structural details of catalysis at near atomic resolution and precise arra...

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Detalles Bibliográficos
Autores principales: Lin, Guowu, Barnes, Christopher O., Weiss, Simon, Dutagaci, Bercem, Qiu, Chenxi, Feig, Michael, Song, Jihnu, Lyubimov, Artem, Cohen, Aina E., Kaplan, Craig D., Calero, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543002/
https://www.ncbi.nlm.nih.gov/pubmed/37790421
http://dx.doi.org/10.1101/2023.09.22.559052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543002/
https://www.ncbi.nlm.nih.gov/pubmed/37790421
http://dx.doi.org/10.1101/2023.09.22.559052

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