Cargando…
Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics
The field of induced proximity therapeutics is in its ascendancy but is limited by a lack of scalable tools to systematically explore effector-target protein pairs in an unbiased manner. Here, we combined Scalable POoled Targeting with a LIgandable Tag at Endogenous Sites (SPOTLITES) for the high-th...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543026/ https://www.ncbi.nlm.nih.gov/pubmed/37790450 http://dx.doi.org/10.21203/rs.3.rs-3161717/v1 |