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Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics
The field of induced proximity therapeutics is in its ascendancy but is limited by a lack of scalable tools to systematically explore effector-target protein pairs in an unbiased manner. Here, we combined Scalable POoled Targeting with a LIgandable Tag at Endogenous Sites (SPOTLITES) for the high-th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Journal Experts
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543026/ https://www.ncbi.nlm.nih.gov/pubmed/37790450 http://dx.doi.org/10.21203/rs.3.rs-3161717/v1 |