Rare variation in noncoding regions with evolutionary signatures contributes to autism spectrum disorder risk

Little is known about the role of noncoding regions in the etiology of autism spectrum disorder (ASD). We examined three classes of noncoding regions: Human Accelerated Regions (HARs), which show signatures of positive selection in humans; experimentally validated neural Vista Enhancers (VEs); and c...

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Detalles Bibliográficos
Autores principales: Shin, Taehwan, Song, Janet H.T., Kosicki, Michael, Kenny, Connor, Beck, Samantha G., Kelley, Lily, Qian, Xuyu, Bonacina, Julieta, Papandile, Frances, Antony, Irene, Gonzalez, Dilenny, Scotellaro, Julia, Bushinsky, Evan M., Andersen, Rebecca E., Maury, Eduardo, Pennacchio, Len A., Doan, Ryan N., Walsh, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543033/
https://www.ncbi.nlm.nih.gov/pubmed/37790480
http://dx.doi.org/10.1101/2023.09.19.23295780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543033/
https://www.ncbi.nlm.nih.gov/pubmed/37790480
http://dx.doi.org/10.1101/2023.09.19.23295780

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