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Small molecule anion carriers facilitate lactate transport in model liposomes and cells

An excessive production of lactate by cancer cells fosters tumor growth and metastasis. Therefore, targeting lactate metabolism and transport offers a new therapeutic strategy against cancer, based on dependency of some cancer cells for lactate as energy fuel or as oncogenic signal. Herein we presen...

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Detalles Bibliográficos
Autores principales: Alonso-Carrillo, Daniel, Arias-Betancur, Alain, Carreira-Barral, Israel, Fontova, Pere, Soto-Cerrato, Vanessa, García-Valverde, María, Pérez-Tomás, Ricardo, Quesada, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543179/
https://www.ncbi.nlm.nih.gov/pubmed/37790273
http://dx.doi.org/10.1016/j.isci.2023.107898