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Ferroportin inhibitor vamifeport ameliorates ineffective erythropoiesis in a mouse model of b-thalassemia with blood transfusions

β-thalassemia is an inherited anemia characterized by ineffective erythropoiesis. Blood transfusions are required for survival in transfusion-dependent b-thalassemia and are also occasionally needed in patients with non-transfusion-dependent β-thalassemia. Patients with transfusion-dependent b-thala...

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Detalles Bibliográficos
Autores principales: Kalleda, Natarajaswamy, Flace, Anna, Altermatt, Patrick, Ingoglia, Giada, Doucerain, Cédric, Nyffenegger, Naja, Dürrenberger, Franz, Manolova, Vania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543196/
https://www.ncbi.nlm.nih.gov/pubmed/37165842
http://dx.doi.org/10.3324/haematol.2022.282328