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Reconstructing Kinetic Models for Dynamical Studies of Metabolism using Generative Adversarial Networks

Kinetic models of metabolism relate metabolic fluxes, metabolite concentrations and enzyme levels through mechanistic relations, rendering them essential for understanding, predicting and optimizing the behaviour of living organisms. However, due to the lack of kinetic data, traditional kinetic mode...

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Detalles Bibliográficos
Autores principales: Choudhury, Subham, Moret, Michael, Salvy, Pierre, Weilandt, Daniel, Hatzimanikatis, Vassily, Miskovic, Ljubisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543203/
https://www.ncbi.nlm.nih.gov/pubmed/37790987
http://dx.doi.org/10.1038/s42256-022-00519-y