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scMultiSim: simulation of single cell multi-omics and spatial data guided by gene regulatory networks and cell-cell interactions

Simulated single-cell data is essential for designing and evaluating computational methods in the absence of experimental ground truth. Existing simulators typically focus on modeling one or two specific biological factors or mechanisms that affect the output data, which limits their capacity to sim...

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Detalles Bibliográficos
Autores principales: Li, Hechen, Zhang, Ziqi, Squires, Michael, Chen, Xi, Zhang, Xiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543280/
https://www.ncbi.nlm.nih.gov/pubmed/37790516
http://dx.doi.org/10.21203/rs.3.rs-3301625/v1