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scMultiSim: simulation of single cell multi-omics and spatial data guided by gene regulatory networks and cell-cell interactions
Simulated single-cell data is essential for designing and evaluating computational methods in the absence of experimental ground truth. Existing simulators typically focus on modeling one or two specific biological factors or mechanisms that affect the output data, which limits their capacity to sim...
Autores principales: | Li, Hechen, Zhang, Ziqi, Squires, Michael, Chen, Xi, Zhang, Xiuwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543280/ https://www.ncbi.nlm.nih.gov/pubmed/37790516 http://dx.doi.org/10.21203/rs.3.rs-3301625/v1 |
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