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Unraveling the intercellular communication disruption and key pathways in Alzheimer’s disease: An integrative study of single-nucleus transcriptomes and genetic association

BACKGROUND: Recently, single-nucleus RNA-seq (snRNA-seq) analyses have revealed important cellular and functional features of Alzheimer’s disease (AD), a prevalent neurodegenerative disease. However, our knowledge regarding intercellular communication mediated by dysregulated ligand-receptor (LR) in...

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Detalles Bibliográficos
Autores principales: Liu, Andi, Fernandes, Brisa S, Citu, Citu, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543294/
https://www.ncbi.nlm.nih.gov/pubmed/37790454
http://dx.doi.org/10.21203/rs.3.rs-3335643/v1