Mucosal prime-boost immunization with live murine pneumonia virus-vectored SARS-CoV-2 vaccine is protective in macaques

Immunization via the respiratory route is predicted to increase the effectiveness of a SARS-CoV-2 vaccine. We evaluated the immunogenicity and protective efficacy of one or two doses of a live-attenuated murine pneumonia virus vector expressing SARS-CoV-2 prefusion-stabilized spike protein (MPV/S-2P...

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Detalles Bibliográficos
Autores principales: Buchholz, Ursula, Kaiser, Jaclyn, Nelson, Christine, Liu, Xueqiao, Park, Hong-Su, Matsuoka, Yumiko, Luongo, Cindy, Santos, Celia, Ahlers, Laura, Herbert, Richard, Moore, Ian, Wilder-Kofie, Temeri, Moore, Rashida, Walker, April, Lijuan, Yang, Munir, Shirin, Teng, I-Ting, Kwong, Peter, Dowdell, Kennichi, Nguyen, Hanh, Kim, JungHyun, Cohen, Jeffrey, Johnson, Reed F., Garza, Nicole, Via, Laura, Barber, Daniel, LE NOUEN, CYRIL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543296/
https://www.ncbi.nlm.nih.gov/pubmed/37790295
http://dx.doi.org/10.21203/rs.3.rs-3278289/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543296/
https://www.ncbi.nlm.nih.gov/pubmed/37790295
http://dx.doi.org/10.21203/rs.3.rs-3278289/v1

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