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ZEPPI: proteome-scale sequence-based evaluation of protein-protein interaction models

We introduce ZEPPI (Z-score Evaluation of Protein-Protein Interfaces), a framework to evaluate structural models of a complex based on sequence co-evolution and conservation involving residues in protein-protein interfaces. The ZEPPI score is calculated by comparing metrics for an interface to those...

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Detalles Bibliográficos
Autores principales: Zhao, Haiqing, Murray, Diana, Petrey, Donald, Honig, Barry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543297/
https://www.ncbi.nlm.nih.gov/pubmed/37790387
http://dx.doi.org/10.21203/rs.3.rs-3289791/v1