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CNS Repopulation by Hematopoietic-Derived Microglia-Like Cells Corrects Progranulin deficiency
Hematopoietic stem cell transplantation can deliver therapeutic proteins to the CNS through donor-derived hematopoietic cells that become microglia-like cells. However, using standard conditioning approaches, hematopoietic stem cell transplantation is currently limited by low and slow engraftment of...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543302/ https://www.ncbi.nlm.nih.gov/pubmed/37790525 http://dx.doi.org/10.21203/rs.3.rs-3263412/v1 |