A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer’s disease patients from controls

BACKGROUND: With the emergence of microglia-modulating therapies there is an urgent need for reliable biomarkers to evaluate microglial activation states. METHODS: Using mouse models and human induced pluripotent stem cell-derived microglia (hiMGL), genetically modified to yield the most opposite ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Pesämaa, Ida, Müller, Stephan A., Robinson, Sophie, Darcher, Alana, Paquet, Dominik, Zetterberg, Henrik, Lichtenthaler, Stefan F., Haass, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543321/
https://www.ncbi.nlm.nih.gov/pubmed/37775827
http://dx.doi.org/10.1186/s13024-023-00657-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543321/
https://www.ncbi.nlm.nih.gov/pubmed/37775827
http://dx.doi.org/10.1186/s13024-023-00657-w

Ejemplares similares