Genotype-based “virtual” metabolomics in a clinical biobank identifies novel metabolite-disease associations

Circulating metabolites act as biomarkers of dysregulated metabolism, and may inform disease pathophysiology. A portion of the inter-individual variability in circulating metabolites is influenced by common genetic variation. We evaluated whether a genetics-based “virtual” metabolomics approach can...

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Detalles Bibliográficos
Autores principales: Bagheri, Minoo, Bombin, Andrei, Shi, Mingjian, Murthy, Venkatesh L., Shah, Ravi, Mosley, Jonathan D., Ferguson, Jane F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543429/
https://www.ncbi.nlm.nih.gov/pubmed/37790512
http://dx.doi.org/10.21203/rs.3.rs-3222588/v2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543429/
https://www.ncbi.nlm.nih.gov/pubmed/37790512
http://dx.doi.org/10.21203/rs.3.rs-3222588/v2

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