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Shared bias in H chain V-J pairing in naive and memory B cells
INTRODUCTION: H chain rearrangement in B cells is a two-step process where first D(H) binds J(H) , and only then V(H) is joined to the complex. As such, there is no direct rearrangement between V(H) and J(H) . RESULTS: Nevertheless, we here show that the V(H) JH combinations frequency in humans devi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543446/ https://www.ncbi.nlm.nih.gov/pubmed/37790930 http://dx.doi.org/10.3389/fimmu.2023.1166116 |