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Gastrodin overcomes chemoresistance via inhibiting Skp2-mediated glycolysis

Aerobic glycolysis, a typical phenotype in human tumors, is associated with tumor progression and chemotherapy resistance. The present study demonstrated that cisplatin-resistant oral squamous cell carcinoma (OSCC) cells exerted a stronger glycolysis ability, which was associated with hexokinase 2 (...

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Detalles Bibliográficos
Autores principales: Xie, Li, Liao, Jinzhuang, Liu, Wenbin, Wang, Ruirui, Li, Xiaoying, Li, Wei, Zhou, Zhongsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543462/
https://www.ncbi.nlm.nih.gov/pubmed/37779163
http://dx.doi.org/10.1038/s41420-023-01648-y