Pulmonary arterial hypertension drugs can partially restore altered angiogenic capacities in bmpr2‐silenced human lung microvascular endothelial cells

Mutations in the bone morphogenetic protein receptor type 2 (bmpr2) gene and signaling pathway impairment are observed in heritable and idiopathic pulmonary arterial hypertension (PAH). In PAH, endothelial dysfunction is currently handled by drugs targeting the endothelin‐1 (ET‐1), nitric oxide (NO)...

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Detalles Bibliográficos
Autores principales: Tielemans, Birger, Wagenaar, Allard, Belge, Catharina, Delcroix, Marion, Quarck, Rozenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543474/
https://www.ncbi.nlm.nih.gov/pubmed/37790139
http://dx.doi.org/10.1002/pul2.12293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543474/
https://www.ncbi.nlm.nih.gov/pubmed/37790139
http://dx.doi.org/10.1002/pul2.12293

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