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Characteristics of FXa-storing platelets in hemophilia B mice and the influence of alcohol on the platelets

Platelet-stored activated blood coagulation factor X (FXa) has great potential in the gene therapy of hemophilia B (HB). However, we still need to understand more about the properties of FXa-storing platelets and how dietary factors affect them. We created transgenic mice called 2bFXa-HB, which had...

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Detalles Bibliográficos
Autores principales: Han, Wenwen, Huang, Rui, Li, Binbin, Liu, Lu, Xu, Wenjue, Zhang, Guowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543635/
https://www.ncbi.nlm.nih.gov/pubmed/37779119
http://dx.doi.org/10.1038/s41598-023-43649-y