Cargando…
Characteristics of FXa-storing platelets in hemophilia B mice and the influence of alcohol on the platelets
Platelet-stored activated blood coagulation factor X (FXa) has great potential in the gene therapy of hemophilia B (HB). However, we still need to understand more about the properties of FXa-storing platelets and how dietary factors affect them. We created transgenic mice called 2bFXa-HB, which had...
Autores principales: | Han, Wenwen, Huang, Rui, Li, Binbin, Liu, Lu, Xu, Wenjue, Zhang, Guowei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543635/ https://www.ncbi.nlm.nih.gov/pubmed/37779119 http://dx.doi.org/10.1038/s41598-023-43649-y |
Ejemplares similares
-
Activated factor X targeted stored in platelets as an effective gene therapy strategy for both hemophilia A and B
por: Wang, Dawei, et al.
Publicado: (2021) -
Influence of Oxidative Stress on Stored Platelets
por: Manasa, K., et al.
Publicado: (2016) -
Antiprothrombin antibodies induce platelet activation: A possible explanation for anti‐FXa therapy failure in patients with antiphospholipid syndrome?
por: Chayoua, Walid, et al.
Publicado: (2021) -
Platelet-Targeted Gene Therapy for Hemophilia
por: Shi, Qizhen
Publicado: (2018) -
Platelets as Modifiers of Clinical Phenotype in Hemophilia
por: Yee, Donald L.
Publicado: (2006)