Cargando…
Proteogenomic identification of an immunogenic antigen derived from human endogenous retrovirus in renal cell carcinoma
CD8(+) T cells can recognize tumor antigens displayed by HLA class I molecules and eliminate tumor cells. Despite their low tumor mutation burden, immune checkpoint blockade (ICB) is often beneficial in patients with renal cell carcinoma (RCC). Here, using a proteogenomic approach, we directly and c...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543709/ https://www.ncbi.nlm.nih.gov/pubmed/37606040 http://dx.doi.org/10.1172/jci.insight.167712 |