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HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease

Cutaneous lupus erythematosus (CLE) is a disfiguring autoimmune skin disease characterized by an inflammatory infiltrate rich in T cells, which are strongly implicated in tissue damage. How these cells adapt to the skin environment and promote tissue inflammation and damage is not known. In lupus ne...

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Detalles Bibliográficos
Autores principales: Little, Alicia J., Chen, Ping-Min, Vesely, Matthew D., Khan, Rahanna N., Fiedler, Jacob, Garritano, James, Maisha, Fahrisa I., McNiff, Jennifer M., Craft, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543720/
https://www.ncbi.nlm.nih.gov/pubmed/37526979
http://dx.doi.org/10.1172/jci.insight.166076