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HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease
Cutaneous lupus erythematosus (CLE) is a disfiguring autoimmune skin disease characterized by an inflammatory infiltrate rich in T cells, which are strongly implicated in tissue damage. How these cells adapt to the skin environment and promote tissue inflammation and damage is not known. In lupus ne...
Autores principales: | Little, Alicia J., Chen, Ping-Min, Vesely, Matthew D., Khan, Rahanna N., Fiedler, Jacob, Garritano, James, Maisha, Fahrisa I., McNiff, Jennifer M., Craft, Joe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543720/ https://www.ncbi.nlm.nih.gov/pubmed/37526979 http://dx.doi.org/10.1172/jci.insight.166076 |
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