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An extensive β(1)-adrenergic receptor gene signaling network regulates molecular remodeling in dilated cardiomyopathies

We investigated the extent, biologic characterization, phenotypic specificity, and possible regulation of a β(1)-adrenergic receptor–linked (β(1)-AR–linked) gene signaling network (β(1)-GSN) involved in left ventricular (LV) eccentric pathologic remodeling. A 430-member β(1)-GSN was identified by mR...

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Detalles Bibliográficos
Autores principales: Tatman, Philip D., Kao, David P., Chatfield, Kathryn C., Carroll, Ian A., Wagner, Jessica A., Jonas, Eric R., Sucharov, Carmen C., Port, J. David, Lowes, Brian D., Minobe, Wayne A., Huebler, Sophia P., Karimpour-Fard, Anis, Rodriguez, Erin M., Liggett, Stephen B., Bristow, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543724/
https://www.ncbi.nlm.nih.gov/pubmed/37606047
http://dx.doi.org/10.1172/jci.insight.169720