Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity

Type 2 diabetes (T2D) is associated with compromised identity of insulin-producing pancreatic islet β cells, characterized by inappropriate production of other islet cell–enriched hormones. Here, we examined how hormone misexpression was influenced by the MAFA and MAFB transcription factors, closely...

Descripción completa

Detalles Bibliográficos
Autores principales: Cha, Jeeyeon, Tong, Xin, Walker, Emily M., Dahan, Tehila, Cochrane, Veronica A., Ashe, Sudipta, Russell, Ronan, Osipovich, Anna B., Mawla, Alex M., Guo, Min, Liu, Jin-hua, Loyd, Zachary A., Huising, Mark O., Magnuson, Mark A., Hebrok, Matthias, Dor, Yuval, Stein, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543725/
https://www.ncbi.nlm.nih.gov/pubmed/37606041
http://dx.doi.org/10.1172/jci.insight.166386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543725/
https://www.ncbi.nlm.nih.gov/pubmed/37606041
http://dx.doi.org/10.1172/jci.insight.166386

Ejemplares similares