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Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity

Type 2 diabetes (T2D) is associated with compromised identity of insulin-producing pancreatic islet β cells, characterized by inappropriate production of other islet cell–enriched hormones. Here, we examined how hormone misexpression was influenced by the MAFA and MAFB transcription factors, closely...

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Detalles Bibliográficos
Autores principales:	Cha, Jeeyeon, Tong, Xin, Walker, Emily M., Dahan, Tehila, Cochrane, Veronica A., Ashe, Sudipta, Russell, Ronan, Osipovich, Anna B., Mawla, Alex M., Guo, Min, Liu, Jin-hua, Loyd, Zachary A., Huising, Mark O., Magnuson, Mark A., Hebrok, Matthias, Dor, Yuval, Stein, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543725/ https://www.ncbi.nlm.nih.gov/pubmed/37606041 http://dx.doi.org/10.1172/jci.insight.166386

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