N-acetylglucosamine-6-O-sulfation on intestinal mucins prevents obesity and intestinal inflammation by regulating gut microbiota

Intestinal mucins play an essential role in the defense against bacterial invasion and the maintenance of gut microbiota, which is instrumental in the regulation of host immune systems; hence, its dysregulation is a hallmark of metabolic disease and intestinal inflammation. However, the mechanism by...

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Detalles Bibliográficos
Autores principales: Abo, Hirohito, Muraki, Aoi, Harusato, Akihito, Imura, Tetsuya, Suzuki, Maki, Takahashi, Kohta, Denning, Timothy L., Kawashima, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543739/
https://www.ncbi.nlm.nih.gov/pubmed/37463055
http://dx.doi.org/10.1172/jci.insight.165944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543739/
https://www.ncbi.nlm.nih.gov/pubmed/37463055
http://dx.doi.org/10.1172/jci.insight.165944

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