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N-acetylglucosamine-6-O-sulfation on intestinal mucins prevents obesity and intestinal inflammation by regulating gut microbiota
Intestinal mucins play an essential role in the defense against bacterial invasion and the maintenance of gut microbiota, which is instrumental in the regulation of host immune systems; hence, its dysregulation is a hallmark of metabolic disease and intestinal inflammation. However, the mechanism by...
Autores principales: | Abo, Hirohito, Muraki, Aoi, Harusato, Akihito, Imura, Tetsuya, Suzuki, Maki, Takahashi, Kohta, Denning, Timothy L., Kawashima, Hiroto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543739/ https://www.ncbi.nlm.nih.gov/pubmed/37463055 http://dx.doi.org/10.1172/jci.insight.165944 |
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