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Lenalidomide improves NKG2D-based CAR-T cell activity against colorectal cancer cells invitro

INTRODUCTION: Although CAR-based immunotherapy is viewed as a promising treatment for tumors, particularly hematological malignancies, solid tumors can pose challenges. It has been suggested that the immunomodulatory medication Lenalidomide (LEN) may increase the effectiveness of CAR T cells in the...

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Detalles Bibliográficos
Autores principales: Zarei, Mahdi, Abdoli, Shahriyar, Farazmandfar, Touraj, Shahbazi, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543764/
https://www.ncbi.nlm.nih.gov/pubmed/37790973
http://dx.doi.org/10.1016/j.heliyon.2023.e20460