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Rational design of an N-terminal cysteine-containing tetrapeptide that inhibits tyrosinase and evaluation of its mechanism of action

There has been a resurgence of interest in bioactive peptides as therapeutic agents. This is particularly interesting for tyrosinase, which can be inhibited by thiol-containing peptides. This work demonstrates that an N-terminal cysteine-containing tetrapeptide can be rationally designed to inhibit...

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Detalles Bibliográficos
Autores principales: Joompang, Anupong, Anwised, Preeyanan, Klaynongsruang, Sompong, Taemaitree, Lapatrada, Wanthong, Anuwat, Choowongkomon, Kiattawee, Daduang, Sakda, Katekaew, Somporn, Jangpromma, Nisachon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543783/
https://www.ncbi.nlm.nih.gov/pubmed/37790858
http://dx.doi.org/10.1016/j.crfs.2023.100598