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Unveiling drug-tolerant and persister-like cells in Leishmania braziliensis lines derived from patients with cutaneous leishmaniasis

INTRODUCTION: Resistance against anti-Leishmania drugs (DR) has been studied for years, giving important insights into long-term adaptations of these parasites to drugs, through genetic modifications. However, microorganisms can also survive lethal drug exposure by entering into temporary quiescence...

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Detalles Bibliográficos
Autores principales: Jara, Marlene, Arevalo, Jorge, Llanos-Cuentas, Alejandro, den Broeck, Frederik Van, Domagalska, Malgorzata Anna, Dujardin, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543814/
https://www.ncbi.nlm.nih.gov/pubmed/37790908
http://dx.doi.org/10.3389/fcimb.2023.1253033