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A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain

BACKGROUND: Epigenetic changes can bring insight into gene regulatory mechanisms associated with disease pathogenicity, including chronicity and increased vulnerability. To date, we are yet to identify genes sensitive to epigenetic regulation that contribute to the maintenance of chronic pain and wi...

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Detalles Bibliográficos
Autores principales: Maiarù, Maria, Acton, Richard J., Woźniak, Eva L., Mein, Charles A., Bell, Christopher G., Géranton, Sandrine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543848/
https://www.ncbi.nlm.nih.gov/pubmed/37777763
http://dx.doi.org/10.1186/s13148-023-01569-8