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Predicting tumour content of liquid biopsies from cell-free DNA

BACKGROUND: Liquid biopsy is a minimally-invasive method of sampling bodily fluids, capable of revealing evidence of cancer. The distribution of cell-free DNA (cfDNA) fragment lengths has been shown to differ between healthy subjects and cancer patients, whereby the distributional shift correlates w...

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Detalles Bibliográficos
Autores principales: Cardner, Mathias, Marass, Francesco, Gedvilaite, Erika, Yang, Julie L., Tsui, Dana W. Y., Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543881/
https://www.ncbi.nlm.nih.gov/pubmed/37777714
http://dx.doi.org/10.1186/s12859-023-05478-8