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Androgen Receptor Variants Confer Castration Resistance in Prostate Cancer by Counteracting Antiandrogen-Induced Ferroptosis

Androgen receptor (AR) inhibition by androgen deprivation and/or antiandrogen administration is the mainstay therapy for advanced prostate cancer. However, most prostate cancers ultimately become resistant to these therapies, indicating the importance of identifying mechanisms driving resistance to...

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Detalles Bibliográficos
Autores principales: Sun, Rui, Yan, Binyuan, Li, Hao, Ding, Donglin, Wang, Liguo, Pang, Jun, Ye, Dingwei, Huang, Haojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543964/
https://www.ncbi.nlm.nih.gov/pubmed/37527336
http://dx.doi.org/10.1158/0008-5472.CAN-23-0285