Targeting Solid Cancers with a Cancer-Specific Monoclonal Antibody to Surface Expressed Aberrantly O-glycosylated Proteins

The lack of antibodies with sufficient cancer selectivity is currently limiting the treatment of solid tumors by immunotherapies. Most current immunotherapeutic targets are tumor-associated antigens that are also found in healthy tissues and often do not display sufficient cancer selectivity to be u...

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Detalles Bibliográficos
Autores principales: Aasted, Mikkel K.M., Groen, Aaron C., Keane, John T., Dabelsteen, Sally, Tan, Edwin, Schnabel, Julia, Liu, Fang, Lewis, Hyeon-Gyu S., Theodoropulos, Constantine, Posey, Avery D., Wandall, Hans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Large Molecule Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543972/
https://www.ncbi.nlm.nih.gov/pubmed/37451822
http://dx.doi.org/10.1158/1535-7163.MCT-23-0221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543972/
https://www.ncbi.nlm.nih.gov/pubmed/37451822
http://dx.doi.org/10.1158/1535-7163.MCT-23-0221

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