Bis-6-amidino-benzothiazole Derivative that Cures Experimental Stage 1 African Trypanosomiasis with a Single Dose

[Image: see text] We designed and synthesized a series of symmetric bis-6-amidino-benzothiazole derivatives with aliphatic central units and evaluated their efficacy against bloodstream forms of the African trypanosome Trypanosoma brucei. Of these, a dicationic benzothiazole compound (9a) exhibited...

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Detalles Bibliográficos
Autores principales: Racané, Livio, Ptiček, Lucija, Kostrun, Sanja, Raić-Malić, Silvana, Taylor, Martin Craig, Delves, Michael, Alsford, Sam, Olmo, Francisco, Francisco, Amanda Fortes, Kelly, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544003/
https://www.ncbi.nlm.nih.gov/pubmed/37722077
http://dx.doi.org/10.1021/acs.jmedchem.3c01051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544003/
https://www.ncbi.nlm.nih.gov/pubmed/37722077
http://dx.doi.org/10.1021/acs.jmedchem.3c01051

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