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Oxetanes in Drug Discovery Campaigns

[Image: see text] The oxetane ring is an emergent, underexplored motif in drug discovery that shows attractive properties such as low molecular weight, high polarity, and marked three-dimensionality. Oxetanes have garnered further interest as isosteres of carbonyl groups and as molecular tools to fi...

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Detalles Bibliográficos
Autores principales: Rojas, Juan J., Bull, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544023/
https://www.ncbi.nlm.nih.gov/pubmed/37676858
http://dx.doi.org/10.1021/acs.jmedchem.3c01101