Empagliflozin Suppresses the Differentiation/Maturation of Human Epicardial Preadipocytes and Improves Paracrine Secretome Profile

Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce epicardial adipose tissue (EAT) in humans, enhancing cardioprotective effects on heart failure and atrial fibrillation. We investigated the direct effect of the SGLT2 inhibitor empagliflozin on human primary epicardial adipocytes and preadipoc...

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Detalles Bibliográficos
Autores principales: Takano, Masayuki, Kondo, Hidekazu, Harada, Taisuke, Takahashi, Masaki, Ishii, Yumi, Yamasaki, Hirochika, Shan, Tong, Akiyoshi, Kumiko, Shuto, Takashi, Teshima, Yasushi, Wada, Tomoyuki, Yufu, Kunio, Sako, Hidenori, Anai, Hirofumi, Miyamoto, Shinji, Takahashi, Naohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research - Clinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544075/
https://www.ncbi.nlm.nih.gov/pubmed/37791312
http://dx.doi.org/10.1016/j.jacbts.2023.05.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544075/
https://www.ncbi.nlm.nih.gov/pubmed/37791312
http://dx.doi.org/10.1016/j.jacbts.2023.05.007

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