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Empagliflozin Suppresses the Differentiation/Maturation of Human Epicardial Preadipocytes and Improves Paracrine Secretome Profile
Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce epicardial adipose tissue (EAT) in humans, enhancing cardioprotective effects on heart failure and atrial fibrillation. We investigated the direct effect of the SGLT2 inhibitor empagliflozin on human primary epicardial adipocytes and preadipoc...
Autores principales: | Takano, Masayuki, Kondo, Hidekazu, Harada, Taisuke, Takahashi, Masaki, Ishii, Yumi, Yamasaki, Hirochika, Shan, Tong, Akiyoshi, Kumiko, Shuto, Takashi, Teshima, Yasushi, Wada, Tomoyuki, Yufu, Kunio, Sako, Hidenori, Anai, Hirofumi, Miyamoto, Shinji, Takahashi, Naohiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544075/ https://www.ncbi.nlm.nih.gov/pubmed/37791312 http://dx.doi.org/10.1016/j.jacbts.2023.05.007 |
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