Identification of a small molecule for enhancing lentiviral transduction of T cells

Genetic modification of cells using viral vectors has shown huge therapeutic benefit in multiple diseases. However, inefficient transduction contributes to the high cost of these therapies. Several transduction-enhancing small molecules have previously been identified; however, some may be toxic to...

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Detalles Bibliográficos
Autores principales: Malach, Paulina, Kay, Charlotte, Tinworth, Chris, Patel, Florence, Joosse, Bryan, Wade, Jennifer, Rosa do Carmo, Marlene, Donovan, Brian, Brugman, Martijn, Montiel-Equihua, Claudia, Francis, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544093/
https://www.ncbi.nlm.nih.gov/pubmed/37790244
http://dx.doi.org/10.1016/j.omtm.2023.101113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544093/
https://www.ncbi.nlm.nih.gov/pubmed/37790244
http://dx.doi.org/10.1016/j.omtm.2023.101113

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