Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy

Mitochondrial dysfunction is suggested to be a major contributor for the progression of heart failure (HF). Here we examined the role of syntaxin 17 (STX17) in the progression of HF. Cardiac-specific Stx17 knockout manifested cardiac dysfunction and mitochondrial damage, associated with reduced leve...

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Detalles Bibliográficos
Autores principales: Xu, Haixia, Wang, Xiang, Yu, Wenjun, Sun, Shiqun, Wu, Ne N., Ge, Junbo, Ren, Jun, Zhang, Yingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research - Preclinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544097/
https://www.ncbi.nlm.nih.gov/pubmed/37791317
http://dx.doi.org/10.1016/j.jacbts.2023.04.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544097/
https://www.ncbi.nlm.nih.gov/pubmed/37791317
http://dx.doi.org/10.1016/j.jacbts.2023.04.006

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