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Mettl1-mediated internal m(7)G methylation of Sptbn2 mRNA elicits neurogenesis and anti-alzheimer’s disease

BACKGROUND: N(7)-methylguanosine (m(7)G) is one of the most conserved modifications in nucleosides impacting mRNA export, splicing, and translation. However, the precise function and molecular mechanism of internal mRNA m(7)G methylation in adult hippocampal neurogenesis and neurogenesis-related Alz...

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Detalles Bibliográficos
Autores principales: Li, Qingfeng, Liu, Hui, Li, Lishi, Guo, Haomin, Xie, Zhihao, Kong, Xuejian, Xu, Jiamin, Zhang, Junlin, Chen, Yunxia, Zhang, Zhongsheng, Liu, Jun, Xuan, Aiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544167/
https://www.ncbi.nlm.nih.gov/pubmed/37779199
http://dx.doi.org/10.1186/s13578-023-01131-2