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Mettl1-mediated internal m(7)G methylation of Sptbn2 mRNA elicits neurogenesis and anti-alzheimer’s disease
BACKGROUND: N(7)-methylguanosine (m(7)G) is one of the most conserved modifications in nucleosides impacting mRNA export, splicing, and translation. However, the precise function and molecular mechanism of internal mRNA m(7)G methylation in adult hippocampal neurogenesis and neurogenesis-related Alz...
Autores principales: | Li, Qingfeng, Liu, Hui, Li, Lishi, Guo, Haomin, Xie, Zhihao, Kong, Xuejian, Xu, Jiamin, Zhang, Junlin, Chen, Yunxia, Zhang, Zhongsheng, Liu, Jun, Xuan, Aiguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544167/ https://www.ncbi.nlm.nih.gov/pubmed/37779199 http://dx.doi.org/10.1186/s13578-023-01131-2 |
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